S. Korean scientists verify presence of “neutralizing antibodies” in COVID-19 patients for first time

Posted on : 2020-04-23 23:11 KST Modified on : 2020-04-23 23:18 KST
Reactivation cases still have virus in respiratory organs, despite presence of antibodies
Plastic screens are installed to form protective barriers between cashiers and customers at a supermarket in Daegu. (Yonhap News)
Plastic screens are installed to form protective barriers between cashiers and customers at a supermarket in Daegu. (Yonhap News)

The antibodies detected in patients where COVID-19 has reactivated are "neutralizing antibodies” that are capable of resisting the virus after infections, an analysis shows. But around half of these patients were found to have the virus still present in their respiratory organs despite the presence of neutralizing antibodies. This marks the first time disease control authorities have verified neutralizing antibodies for the novel coronavirus.

"Interim findings from analytical testing to determine whether the virus could still be detected after antibodies had formed following recovery from coronavirus infection showed that all 25 confirmed patients had formed neutralizing antibodies capable of resisting the virus after infection,” said Korea Centers for Disease Control and Prevention (KCDC) Director Jung Eun-kyeong in a regular briefing on Apr. 22. The South Korean government previously performed neutralizing antibody testing on 25 randomly selected patients who had tested positive for the coronavirus a second time after being declared fully recovered. A neutralizing antibody is a form of antibody that exhibits protective capabilities in terms of resisting viruses following infection.

But 12 of the reactivation cases with neutralizing antibodies -- nearly half -- tested positive in genetic testing for the virus.

"It may be surmised that the virus may not be completely eliminated even after neutralizing antibodies have formed, and that the periods over which it remains in the body may vary from patient to patient,” Jung said, adding that "additional research is currently being performed.”

“Additional culture testing for the virus was performed on 12 patients, but they were found to be negative in primary testing,” she continued. KCDC plans to continue performing neutralizing antibody testing on other patients who test positive a second time. A total of 207 people had been re-diagnosed with the novel coronavirus as of Apr. 22.

Meanwhile, disease control authorities called on senior citizens and children with weak immune systems to receive inoculations for other diseases even amid the coronavirus pandemic.

"Amid the coronavirus outbreak, visits to healthcare institutions have declined, and the Streptococcus pneumoniae inoculation rate for seniors aged 65 and over has fallen to a third of what it was last year,” Jung noted.

"Even amid the coronavirus outbreak, seniors and children should continue to receive safe inoculations while observing infectious disease prevention rules,” she urged. Disease control authorities plan to develop an online and mobile-based reservation system for inoculations to prevent rushes of people receiving them at the same time.

By Kwon Ji-dam, staff reporter

Please direct comments or questions to [english@hani.co.kr]

button that move to original korean article (클릭시 원문으로 이동하는 버튼)

Related stories

Most viewed articles